Medical Surgeon | Azienda Ospedaliera Universitaria delle Marche | Italy
Dr. Francesco De Francesco is an accomplished clinician-scientist specializing in plastic, reconstructive, and regenerative surgery, with a strong academic background in stem cell biology and tissue engineering. His career reflects a balance of clinical expertise, laboratory research, and teaching, enabling him to translate scientific discoveries into therapeutic innovations. His work has focused extensively on adipose-derived stem cells, extracellular vesicles, and their applications in regenerative medicine, particularly in joint and soft tissue repair. Alongside his research, he has played an important role as a medical executive, advancing clinical practices in reconstructive and hand surgery. He has also contributed to academic training, fostering knowledge transfer and supporting the next generation of medical professionals. Recognized with national scientific qualifications and specialization, his profile reflects leadership, dedication, and significant impact in his field. His measurable research influence is demonstrated through Scopus with 3,218 citations, 122 documents, and an h-index of 30.
Profiles: Scopus | Google Scholar | ORCID
Featured Publications
1. V. Tirino, V. Desiderio, F. Paino, A. De Rosa, F. Papaccio, M. La Noce, and F. De Francesco, “Cancer stem cells in solid tumors: an overview and new approaches for their isolation and characterization,” The FASEB Journal, vol. 27, no. 1, pp. 13–24, 2013.
2. V. Tirino, V. Desiderio, R. d’Aquino, F. De Francesco, G. Pirozzi, U. Galderisi, and F. Papaccio, “Detection and characterization of CD133+ cancer stem cells in human solid tumours,” PLoS One, vol. 3, no. 10, p. e3469, 2008.
3. A. Graziano, R. d’Aquino, M. G. C. D. Angelis, F. De Francesco, A. Giordano, and G. Papaccio, “Scaffold’s surface geometry significantly affects human stem cell bone tissue engineering,” Journal of Cellular Physiology, vol. 214, no. 1, pp. 166–172, 2008.
4. F. De Francesco, G. Ricci, F. D’Andrea, G. F. Nicoletti, and G. A. Ferraro, “Human adipose stem cells: from bench to bedside,” Tissue Engineering Part B: Reviews, vol. 21, no. 6, pp. 572–584, 2015.
5. F. De Francesco, V. Tirino, V. Desiderio, G. Ferraro, F. D’Andrea, M. Giuliano, and F. Papaccio, “Human CD34+/CD90+ ASCs are capable of growing as sphere clusters, producing high levels of VEGF and forming capillaries,” PLoS One, vol. 4, no. 8, p. e6537, 2009.