Senior Experimentalist at Yunnan University of Traditional Chinese Medicine, China
He Fangyan is a distinguished researcher specializing in the pharmacodynamics and pharmacokinetics of traditional Chinese medicine. Currently serving as a Senior Experimentalist at Yunnan University of Traditional Chinese Medicine, she has led multiple high-impact studies focusing on ischemic stroke mechanisms and brain pharmacokinetics. With a commitment to advancing neuropharmacology, she has secured prestigious research grants, contributed to key scientific advancements, and developed innovative methodologies in cerebral ischemia treatment. Her expertise extends to drug metabolism, blood-brain barrier protection, and targeted drug delivery, making her a prominent figure in the field. Through her patents, publications, and ongoing research, she continues to bridge the gap between traditional Chinese medicine and modern pharmacological science.
Professional Profile
Education
He Fangyan holds an advanced degree in pharmacology and traditional Chinese medicine research, equipping her with interdisciplinary expertise in both experimental and clinical pharmacokinetics. She has undergone rigorous training in drug absorption, metabolism, and pharmacodynamics, particularly focusing on ischemic stroke therapies. Her academic background includes specialized studies in cerebral ischemia-reperfusion injury and neuroprotection, which laid the foundation for her innovative research contributions. She has further enhanced her knowledge through postgraduate research projects, technical training in pharmacological analysis, and collaborations with leading scientists in neurological drug development. Her education has provided her with a strong analytical and methodological foundation, enabling her to conduct cutting-edge research in traditional Chinese medicine’s role in stroke management.
Professional Experience
With extensive experience in experimental pharmacology and neuroscience, He Fangyan has held a senior research position at Yunnan University of Traditional Chinese Medicine, leading multiple research projects funded by national and provincial grants. She has played a pivotal role in advancing traditional Chinese medicine applications for stroke treatment, particularly through the study of Gastrodia’s neuroprotective effects. Over the years, she has worked on high-impact studies integrating brain microdialysis, PK/PD modeling, and oxidative stress mechanisms. In addition to academic research, she has contributed to methodology development in neuropharmacology, ensuring precise drug targeting and evaluation of traditional medicine compounds. Her professional contributions also extend to mentoring young researchers and fostering interdisciplinary collaborations, strengthening the field of pharmacokinetics and neuroprotection.
Research Interests
He Fangyan’s primary research interests revolve around cerebral ischemia, blood-brain barrier protection, and pharmacokinetics of traditional Chinese medicine compounds. She is particularly focused on understanding the mechanisms of ischemic stroke and the therapeutic potential of Gastrodia-derived compounds in treating oxidative stress-induced brain damage. Her studies employ microdialysis techniques, drug metabolism analysis, and neuroprotective compound development, making significant contributions to stroke research. She is also deeply invested in the translation of traditional Chinese medicine principles into modern pharmacological applications, aiming to bridge ancient remedies with contemporary scientific methodologies. Additionally, she explores novel drug delivery systems and prodrug mechanisms, ensuring targeted treatment with minimal side effects for cerebrovascular diseases.
Awards and Honors
He Fangyan has been recognized for her outstanding contributions to traditional Chinese medicine research and neuropharmacology. She has received funding from prestigious institutions such as the National Natural Science Foundation of China and the Yunnan Science and Technology Department, reflecting the significance of her work. Her patented innovations in cerebral ischemia treatment have earned acclaim, contributing to advancements in stroke therapy. She has also published extensively in SCI-indexed journals, further solidifying her academic reputation. As a key figure in pharmacokinetics and stroke research, she has been invited to speak at academic conferences and collaborate on national research initiatives. Her dedication to scientific progress and innovation continues to garner recognition, positioning her as a leading researcher in the field of traditional Chinese medicine and neuroscience.
Conclusion
He Fangyan is a strong candidate for the Best Researcher Award due to extensive contributions to pharmacokinetics and stroke research, significant grant funding, patents, and high-impact journal publications. Strengthening industry ties, international collaborations, and academic outreach could further solidify eligibility for top-tier research awards.
Publications Top Noted
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He, F., Feng, J., Sun, H., Xu, Y., Yan, H., Song, X., Wang, Y., Li, X., & Lin, Q. (2024). Protective Effect of Protocatechuic Aldehyde on Cerebral Ischemia/Reperfusion Injury in Rats through Blood–Brain Barrier Protection. Bulletin of Experimental Biology and Medicine. https://doi.org/10.1007/s10517-024-06264-z
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He, F., Xu, C., Feng, J., Sun, H., Yan, M., Yang, Q., Zhou, X., Yang, J., & Lin, Q. (2024). Pharmacokinetics of 4-Hydroxybenzaldehyde in Normal and Cerebral Ischemia–Reperfusion Injury Rats Based on Microdialysis Technique. European Journal of Drug Metabolism and Pharmacokinetics. https://doi.org/10.1007/s13318-023-00863-3
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He, F., Ma, C., Feng, J., Li, X., Xia, S., Lin, Q., Dai, R., & He, F. (2021). Angiogenesis effects of 4-methoxy benzyl alcohol on cerebral ischemia-reperfusion injury via regulation of VEGF-Ang/Tie2 balance. Canadian Journal of Physiology and Pharmacology. https://doi.org/10.1139/cjpp-2021-0118
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He, F., Dai, R., Zhou, X., Li, X., Song, X., Yan, H., Meng, Q., Yang, C., & Lin, Q. (2019). Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury. Biomedicine & Pharmacotherapy. https://doi.org/10.1016/j.biopha.2019.109260
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He, F., Duan, X., Dai, R., Li, Y., & Lin, Q. (2017). Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood–Brain Barrier after Cerebral Ischemia Reperfusion Injury. Journal of Stroke and Cerebrovascular Diseases. https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.01.018