Prof. Magdalena Zernicka-Goetz | Stem cell biology | Breakthrough Innovator Award
Professor, California Institute of Technology,ย United States
Magdalena Zernicka-Goetz, Ph.D., is a distinguished Bren Professor of Biology and Biological Engineering at the California Institute of Technology (Caltech), USA, and a Professor in Mammalian Development and Stem Cell Biology at the University of Cambridge, UK. ๐ With an extensive background in physiology, development, and neuroscience, she has made remarkable contributions to the field. ๐งฌ As a Fellow of Sidney Sussex College, Cambridge, she balances her academic pursuits with a personal life, being a proud mother to Natalia (born 2001) and Szymon (born 2007). ๐ Driven by her passion for science and family, she continues to inspire in both academic and personal realms. ๐
Profile
Education
Magdalena Zernicka-Goetz’s academic journey is a testament to her commitment and excellence. ๐ She earned her Master of Science in Developmental Biology with summa cum laude honors from the University of Warsaw in 1988. ๐ Continuing her pursuit of knowledge, she completed her Ph.D. in Developmental Biology of Mammals at the same institution under the guidance of Prof. Andrzej Tarkowski. ๐งฌ Her scholarly pursuits extended internationally with a SOROS Foundation Fellowship at the University of Oxford in 1990-1991 and an EMBO Fellowship at the University of Cambridge in 1995-1997 under the mentorship of Prof. Chris Graham and Prof. Martin Evans, respectively. ๐ This diverse academic background laid the foundation for her groundbreaking contributions in developmental biology. ๐
Awards and Honours
Magdalena Zernicka-Goetz stands as a distinguished figure in the scientific community, adorned with numerous accolades that highlight her exceptional contributions to stem cell research and developmental biology. ๐ Among her recent honors, the Ogawa-Yamanaka Stem Cell Prize in 2023 and the Edwin G. Conklin Medal in 2022 underscore her groundbreaking work. ๐ The NIH Directorโs Pioneer Award in 2020 and her tenure as the Chih-Ye Professor at the State Key Laboratory of Stem Cell and Reproductive Biology in Beijing further emphasize her global impact. ๐ Over the years, she has garnered recognition for her lifetime contributions, including COGI and RBMO awards, the International Foundation IVI Award, and being the Peopleโs Vote winner for Scientific Breakthrough of the Year in 2016. ๐ Her journey, marked by prestigious fellowships and awards, reflects a career dedicated to advancing scientific knowledge.
Professional Historyย
Magdalena Zernicka-Goetz’s illustrious career has been marked by significant milestones and academic achievements. ๐ Since 2010, she has held the position of Professor in Mammalian Development and Stem Cell Biology at the University of Cambridge, contributing to the Department of Physiology, Development & Neuroscience. ๐ Her commitment to academic excellence was acknowledged with tenure as Reader in Developmental Biology from 2007 to 2010. ๐ Zernicka-Goetz’s leadership flourished as a Group Leader at the Wellcome Trust/Cancer Research Institute from 2003, and her role as a Wellcome Trust Senior Research Fellow from 2003 to 2023 underscores her influential presence in scientific research. ๐ Additionally, she became a Fellow of Sidney Sussex College in 2016, further enriching the academic tapestry at Cambridge. ๐
Publications Top Notes
- “Specific interference with gene function by double-stranded RNA in early mouse development”
- Publication Link: Nature Cell Biology
- Cited By (Year): 1184 (2000)
- “G&T-seq: parallel sequencing of single-cell genomes and transcriptomes”
- Publication Link: Nature Methods
- Cited By (Year): 738 (2015)
- “Self-organization of the in vitro attached human embryo”
- Publication Link: Nature
- Cited By (Year): 656 (2016)
- “Histone arginine methylation regulates pluripotency in the early mouse embryo”
- Publication Link: Nature
- Cited By (Year): 648 (2007)
- “Self-organization of the human embryo in the absence of maternal tissues”
- Publication Link: Nature Cell Biology
- Cited By (Year): 635 (2016)
- “A genome-wide study of gene activity reveals developmental signaling pathways in the preimplantation mouse embryo”
- Publication Link: Developmental Cell
- Cited By (Year): 597 (2004)
- “Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation”
- Publication Link: Cell
- Cited By (Year): 430 (2014)
- “Heterogeneity in Oct4 and Sox2 targets biases cell fate in 4-cell mouse embryos”
- Publication Link: Cell
- Cited By (Year): 414 (2016)
- “Citrullination regulates pluripotency and histone H1 binding to chromatin”
- Publication Link: Nature
- Cited By (Year): 412 (2014)
- “Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro”
- Publication Link: Science
- Cited By (Year): 399 (2017)