Young-Hee Kang | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Prof. Dr. Young-Hee Kang | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Professor at Hallym University, South Korea

Dr. Young-Hee Kang, Ph.D., is a distinguished researcher and academic in the field of nutrition and metabolic diseases. With a career spanning over three decades, she has made significant contributions to understanding the role of nutrition in chronic diseases such as atherosclerosis, diabetes, osteoporosis, and respiratory disorders. Currently serving as a Chair Professor at Hallym University, Dr. Kang has held various leadership positions, including Dean of Academic Affairs, Brain Korea 21 Plus Team Director, and President of the Korean Nutrition Society. Her research has been widely recognized through prestigious awards, and she has been actively involved in national and international scientific communities. Through her extensive work in nutritional science, she has influenced both academic research and public health policies, making her one of the leading figures in the field.

Professional Profile

Education

Dr. Kang completed her Ph.D. in Nutrition from Rutgers University, USA, in 1988, following her M.Sc. in Nutrition from Drexel University and a B.Sc. in Food and Nutrition from Seoul National University, Korea. Her academic journey reflects a strong foundation in nutrition science and metabolism, which has guided her research and teaching career. Throughout her education, she gained expertise in biochemical and clinical nutrition, which later became the cornerstone of her work in understanding oxidative stress, inflammatory diseases, and metabolic disorders. Her studies in the U.S. and Korea have provided her with a global perspective on nutrition research, enabling her to contribute to both local and international scientific advancements in public health and disease prevention.

Professional Experience

Dr. Kang has an impressive academic and research career, having held various leadership positions at Hallym University, where she has served as Department Chairperson, Dean of Academic Affairs, and Director of Brain Korea 21 Research Teams. She has also contributed as a visiting scholar at the University of Hospital Grosshadern in Germany and the Uniformed Services University of the Health Sciences (USUHS) in the U.S. Her professional experience extends beyond academia, as she has been involved in editorial boards, scientific committees, and policy advisory groups, ensuring that her research findings translate into real-world applications. As a Fellow of The Korean Academy of Science and Technology, she has played a key role in advancing research, education, and innovation in nutrition science, positioning herself as a thought leader in the field.

Research Interests

Dr. Kang’s research focuses on the role of nutrition in metabolic diseases, with particular emphasis on atherosclerosis, diabetic complications, osteoporosis, and sarcopenia. Her work explores the mechanisms of lipoprotein oxidation, endothelial apoptosis, and macrophage phenotypes, providing critical insights into how diet influences chronic disease progression. Additionally, she has investigated plant-based bioactive compounds and their therapeutic effects on inflammation, oxidative stress, and metabolic disorders. Her research has led to the development of novel dietary interventions, advancing the understanding of functional foods and personalized nutrition. Through interdisciplinary collaborations, she continues to explore innovative approaches to disease prevention and health promotion, impacting both academia and public health policy.

Awards and Honors

Dr. Kang has received numerous prestigious awards for her outstanding contributions to nutrition science. Notable honors include the Korean Nutrition Society Achievement Award (2021), the Korean Society of Food Science and Nutrition Academic Award (2020), and the World Vision President Award (2018). She has also been recognized by The Korean Academy of Science and Technology as a Fellow (2014) and received the Ministry of Agriculture, Food, and Rural Affairs Minister’s Award (2013) for her contributions to food and health research. Additionally, her work has been highlighted by Faculty of 1000 Biology for its impact on nutrition and metabolism research. With a distinguished record of accomplishments, Dr. Kang remains a leading figure in the field, continuously advancing scientific knowledge and improving global health through her research.

Conclusion

Dr. Young-Hee Kang is a highly accomplished researcher with exceptional contributions to nutrition, metabolic diseases, and public health. Her strong research impact, leadership, and numerous awards make her a strong candidate for the Best Researcher Award. Further international recognition and industry collaborations could further solidify her standing as a leading global scientist.

Publications Top Noted

  • Kim, D.Y., Park, S.-H., Yoon, Z., Kim, J., Kang, M.-K., & Kang, Y.-H. (2024). Eucalyptol ameliorates retinal microvascular defects through modulating ER stress and Angiopoietin–Tie signaling in diabetic eyes. International Journal of Molecular Sciences. DOI: 10.3390/ijms25147826

  • Oh, M.-S., Kim, S.-I., Sim, Y.E., Park, S.-H., Kang, M.-K., Kang, I.-J., Sung, L.S., & Kang, Y.-H. (2023). Cirsium Setidens water extracts containing linarin block estrogen deprivation-induced bone loss in mice. International Journal of Molecular Sciences. DOI: 10.3390/ijms24021620

  • Kim, S.-I., Park, S.-H., Na, W., Shin, Y.C., Oh, M.-S., Sim, Y.E., Zheng, Y., Kim, A.H., Kang, I.-J., & Kang, Y.-H. (2022). Dietary collagen hydrolysates retard estrogen deficiency-induced bone loss through blocking osteoclastic activation and enhancing osteoblastic matrix mineralization. Biomedicines. DOI: 10.3390/biomedicines10061382

  • Na, W., Kang, M.-K., Park, S.-H., Kim, D.Y., Oh, S.Y., Oh, M.-S., Park, S., Kang, I.-J., & Kang, Y.-H. (2021). Aesculetin accelerates osteoblast differentiation and matrix-vesicle-mediated mineralization. International Journal of Molecular Sciences. DOI: 10.3390/ijms222212391

  • Kang, M.-K., Kim, D.-Y., Oh, H., Kim, S.-I., Oh, S.-Y., Na, W., Park, S.-H., Park, K., Kim, J.-I., Kim, A.-H., et al. (2021). Dietary collagen hydrolysates ameliorate furrowed and parched skin caused by photoaging in hairless mice. International Journal of Molecular Sciences. DOI: 10.3390/ijms22116137

  • Lee, E.-J., Na, W., Kang, M.-K., Kim, Y.-H., Kim, D.-Y., Oh, H., Kim, S.-I., Oh, S.-Y., Park, S., Park, K., et al. (2021). Hydroxycoumarin Scopoletin inhibits bone loss through enhancing induction of bone turnover markers in a mouse model of type 2 diabetes. Biomedicines. DOI: 10.3390/biomedicines9060648

  • Kim, Y.-H., Kang, M.-K., Lee, E.-J., Kim, D.-Y., Oh, H., Kim, S.-I., Oh, S.-Y., Na, W., Shim, J.-H., Kang, I.-J., et al. (2021). Astragalin inhibits cigarette smoke-induced pulmonary thrombosis and alveolar inflammation and disrupts PAR activation and oxidative stress-responsive MAPK-signaling. International Journal of Molecular Sciences. DOI: 10.3390/ijms22073692

  • Oh, S.-Y., Kim, Y.-H., Kang, M.-K., Lee, E.-J., Kim, D.-Y., Oh, H., Kim, S.-I., Na, W., Kang, I.-J., & Kang, Y.-H. (2021). Aesculetin inhibits airway thickening and mucus overproduction induced by urban particulate matter through blocking inflammation and oxidative stress involving TLR4 and EGFR. Antioxidants. DOI: 10.3390/antiox10030494

  • Na, W., Lee, E.-J., Kang, M.-K., Kim, Y.-H., Kim, D.-Y., Oh, H., Kim, S.-I., Oh, S.-Y., & Kang, Y.-H. (2020). Aesculetin inhibits osteoclastic bone resorption through blocking ruffled border formation and lysosomal trafficking. International Journal of Molecular Sciences. DOI: 10.3390/ijms21228581

  • Kang, M.-K., Kim, S.-I., Oh, S.-Y., Na, W., & Kang, Y.-H. (2020). Tangeretin ameliorates glucose-induced podocyte injury through blocking epithelial to mesenchymal transition caused by oxidative stress and hypoxia. International Journal of Molecular Sciences. DOI: 10.3390/ijms21228577

  • Kim, D.Y., Kang, M.-K., Lee, E.-J., Kim, Y.-H., Oh, H., Kim, S.-I., Oh, S.-Y., Na, W., & Kang, Y.-H. (2020). Eucalyptol inhibits amyloid-β-induced barrier dysfunction in glucose-exposed retinal pigment epithelial cells and diabetic eyes. Antioxidants. DOI: 10.3390/antiox9101000

  • Oh, S.-Y., Kim, Y.-H., Kang, M.-K., Lee, E.-J., Kim, D.-Y., Oh, H., Kim, S.-I., Na, W., & Kang, Y.-H. (2020). Aesculetin attenuates alveolar injury and fibrosis induced by close contact of alveolar epithelial cells with blood-derived macrophages via IL-8 signaling. International Journal of Molecular Sciences. DOI: 10.3390/ijms21155518

  • Oh, H., Park, S.-H., Kang, M.-K., Kim, Y.-H., Lee, E.-J., Kim, D.-Y., Kim, S.-I., Oh, S.-Y., Na, W., Sung, L.S., et al. (2020). Asaronic acid inhibited glucose-triggered M2-phenotype shift through disrupting the formation of coordinated signaling of IL-4Rα-Tyk2-STAT6 and GLUT1-Akt-mTOR-AMPK. Nutrients. DOI: 10.3390/nu12072006

  • Lee, E.-J., Kang, M.-K., Kim, Y.-H., Kim, D.-Y., Oh, H., Kim, S.-I., Oh, S.-Y., Na, W., & Kang, Y.-H. (2020). Coumarin ameliorates impaired bone turnover by inhibiting the formation of advanced glycation end products in diabetic osteoblasts and osteoclasts. Biomolecules. DOI: 10.3390/biom10071052

 

Nicolas Carels | Biochemistry | Best Researcher Award

Dr. Nicolas Carels | Biochemistry | Best Researcher Award

Scientist, Fondation Oswaldo Cruz, Brazil

Nicolas Carels is a distinguished Specialist in Science and Technology, focused on Production and Innovation in Public Health at the Fundação Oswaldo Cruz in Brazil. With a robust background in bioinformatics and genomics, he leads cutting-edge research initiatives aimed at advancing public health solutions. 🌍💻

Publication Profile

ORCID

Strengths for the Award

  1. Extensive Experience: Nicolas has over 15 years of research experience in bioinformatics and genomics, including leadership roles at Fundação Oswaldo Cruz, which enhances his credibility and influence in the field.
  2. Diverse Research Contributions: His work spans multiple areas, including public health, sustainable development, and molecular genetics, showcasing a broad application of his expertise. His recent publications on cancer research demonstrate his engagement with pressing global health challenges.
  3. Strong Educational Background: Holding multiple PhDs in biotechnology and phytopathology, along with a master’s degree in management, he combines scientific rigor with practical management skills.
  4. Multilingual Communication: Proficient in several languages (French, English, Italian, Portuguese, and Spanish), Nicolas can communicate effectively in diverse settings, facilitating international collaboration.
  5. Innovative Research Approaches: His use of advanced methodologies (e.g., neural networks, bioinformatics tools) reflects a commitment to leveraging technology in research, leading to impactful findings.

Areas for Improvement

  1. Project Management Experience: While he has experience managing small teams, expanding his skills in larger project management could enhance his leadership capabilities.
  2. Broader Public Engagement: Increasing visibility through public engagement, such as outreach programs or community workshops, could amplify the impact of his research on society.
  3. Interdisciplinary Collaboration: Encouraging more collaborations outside his primary fields could introduce fresh perspectives and innovative solutions to his work.

 

Education

Nicolas earned his European Doctorate in Biotechnology, where he honed skills in phytopathology, molecular genetics, and bioinformatics. He also holds a PhD in Life Science from Université Pierre et Marie Curie, alongside a Master’s in Management from CEPAC. His academic journey reflects a deep commitment to integrating science and management principles. 🎓📚

Experience

With over 20 years of experience, Nicolas has held prominent research roles in various esteemed institutions. His current position involves leading the bioinformatics platform at CDTS, where he applies his expertise in genomic analysis. He has also contributed to notable projects involving gene identification and genome annotation across multiple organisms. 🧬🔬

Research Focus

Nicolas’s research primarily revolves around bioinformatics applications in public health, including the analysis of infectious and chronic diseases. He employs innovative computational methods to enhance our understanding of disease mechanisms and therapeutic strategies, showcasing his dedication to addressing critical health challenges. 📊🧪

Awards and Honours

Throughout his career, Nicolas has received various recognitions for his contributions to science, reflecting his impact on the field of bioinformatics. His work is not only well-respected but also influential in shaping future research directions. 🏆✨

Publication Highlights

Optimizing therapeutic targets for breast cancer using boolean network models (2024) – Comput Biol Chem

Bioinformatics of infectious and chronic diseases at the Center for Technological Development in Health of Fiocruz (2024) – Journal of Information and Data Management

Unveiling the dynamics behind glioblastoma multiforme single-cell data heterogeneity (2024) – Int. J. Mol. Sci.

Assessing RNA-Seq workflow methodologies using Shannon entropy (2024) – Biology

Structural characterization of heat shock protein 90β and molecular interactions with geldanamycin and ritonavir: A computational study (2024) – Int. J. Mol. Sci.

Conclusion

Nicolas Carels exemplifies the qualities of a strong candidate for the Best Researcher Award. His extensive experience, significant contributions to bioinformatics and public health, and innovative approaches to complex problems position him as a leader in his field. By addressing areas for improvement, he can further enhance his impact and inspire future researchers.

Anumesh Pathak | Biochemistry | Best Faculty Award

Dr. Anumesh Pathak | Biochemistry | Best Faculty Award

Senior Demonstrator, DR. RMLIMS, India

👨‍🔬 Dr. Anumesh K Pathak, a dedicated Ph.D. in Biochemistry, currently serves as a Senior Resident in the Department of Biochemistry at Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India. With a passion for molecular biology, he imparts knowledge to medical students, leading experiments and projects focusing on Alzheimer’s, T2DM, and kidney diseases. His expertise extends to executing in vivo studies, utilizing mouse and rat models. Proficient in various molecular and cell biology techniques, including DNA/RNA extraction, qPCR, Western Blot, immunohistochemistry, ELISA, Microarray, GC-MS/MS, and ICP-MS, Dr. Pathak actively contributes to advancing medical research. 🧪🔬

Profile

google scholar

researchgate

Experience

👨‍🔬 As a diligent Senior Resident in the Department of Biochemistry at Dr. Ram Manohar Lohia Institute of Medical Sciences since December 2023, I contribute significantly to molecular research. My role involves mentoring and conducting experiments for medical students, focusing on Alzheimer’s, T2DM, and kidney diseases. Previously, as an Applications Biochemist at the Central Research Laboratory (January 2022 – November 2023), I conducted impactful GC-MS/MS studies on pesticides and food additives. During my tenure as a Senior Research Fellow in the Department of Pathology (November 2018 – November 2021), I actively participated in research endeavors, ensuring lab safety and contributing to scientific publications. 🧪🔬

Education

🎓 Completing my Doctoral of Philosophy with a focus on the “Role of Glutathione S-transferase Genotypes in Signal Integration by GSTP1-JNK, and p53 Pathway in Non-Small Cell Lung Carcinoma” at the Department of Pathology, Dr. Ram Manohar Lohia Institute of Medical Sciences, in collaboration with BBD University, Lucknow (2015-2022), reflects my commitment to advanced medical research. My M.Sc. project at King George’s Medical University delved into an “Age-Dependent study of Aluminum Toxicity in Liver, Kidney, and Brain of male albino rats” (Feb. 2009 – June. 2009). Holding an M.Sc. in Biochemistry from B. U. University Bhopal and a B.Sc. in Chemistry and Botany from V. B. S. Purvanchal University Jaunpur(U.P.), I have consistently demonstrated academic excellence. 🧪🔬🎓

Research Focus

🔬 He research focuses on elucidating the intricate mechanisms underlying the synergistic effects of novel compounds in combating ovarian adenocarcinomas. The study, “Synergistic effect of piperine and paclitaxel on cell fate via cyt-c, Bax/Bcl-2-caspase-3 pathway in ovarian adenocarcinomas SKOV-3 cells” (European Journal of Pharmacology, 2016), explores the interplay of cyt-c, Bax/Bcl-2, and caspase-3 pathways. Additionally, my work extends to innovative therapeutic strategies, as demonstrated in “Synergistic effect of graphene oxide coated nanotised apigenin with paclitaxel (GO-NA/PTX): A ROS dependent mitochondrial mediated apoptosis in ovarian cancer” (Anti-Cancer Agents in Medicinal Chemistry, 2017). These studies contribute valuable insights into potential treatment modalities for ovarian cancer. 🔍🧪

Publications Top Notes

  1. “Synergistic effect of piperine and paclitaxel on cell fate via cyt-c, Bax/Bcl-2-caspase-3 pathway in ovarian adenocarcinomas SKOV-3 cells”
    • Authors: MK Pal, SP Jaiswar, AK Srivastav, S Goyal, A Dwivedi, A Verma, J Singh, …
    • Published in: European Journal of Pharmacology
    • Year: 2016
    • Link
    • Cited by: 57
  2. “Synergistic effect of graphene oxide coated nanotised apigenin with paclitaxel (GO-NA/PTX): A ROS dependent mitochondrial mediated apoptosis in ovarian cancer”
    • Authors: MK Pal, SP Jaiswar, A Dwivedi, S Goyal, VN Dwivedi, AK Pathak, …
    • Published in: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …
    • Year: 2017
    • Link
    • Cited by: 26
  3. “Lithium potentiate oxidative burden and reduced antioxidant status in different rat organs system”
    • Authors: DK Joshi, DS Chauhan, AK Pathak, S Mishra, M Choudhary, VP Singh, …
    • Published in: Int J Toxicol Pharmacol Res
    • Year: 2013
    • Link
    • Cited by: 9
  4. “Fluoride induces DNA damage and cytotoxicity in human hepatocellular carcinoma cells”
    • Authors: A Verma, D Ali, AK Pathak
    • Published in: Toxicological & Environmental Chemistry
    • Year: 2017
    • Link
    • Cited by: 8
  5. “Dynamic Changes in Circulatory Cytokines and Chemokines Levels in Mild to Severe COVID-19 Patients”
    • Authors: V Tiwari, J Agarwal, AK Pathak, S Singh
    • Published in: Indian Journal of Clinical Biochemistry
    • Year: 2023
    • Link
    • Cited by: 7

 

Biochemistry

Introduction of Biochemistry 

Biochemistry research focuses on the chemical processes and compounds that occur within living organisms, aiming to understand the molecular basis of life. It explores the structure, function, and interactions of biomolecules like proteins, nucleic acids, lipids, and carbohydrates to decipher fundamental biological mechanisms.

Protein Structure and Function

Investigating the 3D structure and function of proteins, critical for understanding their roles in biological processes, diseases, drug development, and enzyme kinetics.

Enzyme Mechanisms and Regulation

Studying the catalytic activities, kinetics, and regulation of enzymes, which are essential for metabolic pathways, signal transduction, and maintaining cellular homeostasis.

Genomics and Proteomics

Analyzing the complete set of genes (genomics) and proteins (proteomics) within an organism to comprehend biological functions, relationships, and how they are altered in health and disease.

Metabolism and Metabolic Disorders

Exploring metabolic pathways that govern energy production, storage, and utilization, as well as investigating metabolic disorders such as diabetes and metabolic syndrome to develop targeted therapies.

Nucleic Acid Biochemistry

Studying the structure, function, replication, and transcription of DNA and RNA molecules, fundamental to genetics, gene expression, and understanding hereditary traits and diseases.