Mrs. fangyan He | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

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Mrs. fangyan He | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Senior Experimentalist at Yunnan University of Traditional Chinese Medicine, China

He Fangyan is a distinguished researcher specializing in the pharmacodynamics and pharmacokinetics of traditional Chinese medicine. Currently serving as a Senior Experimentalist at Yunnan University of Traditional Chinese Medicine, she has led multiple high-impact studies focusing on ischemic stroke mechanisms and brain pharmacokinetics. With a commitment to advancing neuropharmacology, she has secured prestigious research grants, contributed to key scientific advancements, and developed innovative methodologies in cerebral ischemia treatment. Her expertise extends to drug metabolism, blood-brain barrier protection, and targeted drug delivery, making her a prominent figure in the field. Through her patents, publications, and ongoing research, she continues to bridge the gap between traditional Chinese medicine and modern pharmacological science.

Professional Profile

Education

He Fangyan holds an advanced degree in pharmacology and traditional Chinese medicine research, equipping her with interdisciplinary expertise in both experimental and clinical pharmacokinetics. She has undergone rigorous training in drug absorption, metabolism, and pharmacodynamics, particularly focusing on ischemic stroke therapies. Her academic background includes specialized studies in cerebral ischemia-reperfusion injury and neuroprotection, which laid the foundation for her innovative research contributions. She has further enhanced her knowledge through postgraduate research projects, technical training in pharmacological analysis, and collaborations with leading scientists in neurological drug development. Her education has provided her with a strong analytical and methodological foundation, enabling her to conduct cutting-edge research in traditional Chinese medicine’s role in stroke management.

Professional Experience

With extensive experience in experimental pharmacology and neuroscience, He Fangyan has held a senior research position at Yunnan University of Traditional Chinese Medicine, leading multiple research projects funded by national and provincial grants. She has played a pivotal role in advancing traditional Chinese medicine applications for stroke treatment, particularly through the study of Gastrodia’s neuroprotective effects. Over the years, she has worked on high-impact studies integrating brain microdialysis, PK/PD modeling, and oxidative stress mechanisms. In addition to academic research, she has contributed to methodology development in neuropharmacology, ensuring precise drug targeting and evaluation of traditional medicine compounds. Her professional contributions also extend to mentoring young researchers and fostering interdisciplinary collaborations, strengthening the field of pharmacokinetics and neuroprotection.

Research Interests

He Fangyan’s primary research interests revolve around cerebral ischemia, blood-brain barrier protection, and pharmacokinetics of traditional Chinese medicine compounds. She is particularly focused on understanding the mechanisms of ischemic stroke and the therapeutic potential of Gastrodia-derived compounds in treating oxidative stress-induced brain damage. Her studies employ microdialysis techniques, drug metabolism analysis, and neuroprotective compound development, making significant contributions to stroke research. She is also deeply invested in the translation of traditional Chinese medicine principles into modern pharmacological applications, aiming to bridge ancient remedies with contemporary scientific methodologies. Additionally, she explores novel drug delivery systems and prodrug mechanisms, ensuring targeted treatment with minimal side effects for cerebrovascular diseases.

Awards and Honors

He Fangyan has been recognized for her outstanding contributions to traditional Chinese medicine research and neuropharmacology. She has received funding from prestigious institutions such as the National Natural Science Foundation of China and the Yunnan Science and Technology Department, reflecting the significance of her work. Her patented innovations in cerebral ischemia treatment have earned acclaim, contributing to advancements in stroke therapy. She has also published extensively in SCI-indexed journals, further solidifying her academic reputation. As a key figure in pharmacokinetics and stroke research, she has been invited to speak at academic conferences and collaborate on national research initiatives. Her dedication to scientific progress and innovation continues to garner recognition, positioning her as a leading researcher in the field of traditional Chinese medicine and neuroscience.

Conclusion

He Fangyan is a strong candidate for the Best Researcher Award due to extensive contributions to pharmacokinetics and stroke research, significant grant funding, patents, and high-impact journal publications. Strengthening industry ties, international collaborations, and academic outreach could further solidify eligibility for top-tier research awards.

Publications Top Noted

  • He, F., Feng, J., Sun, H., Xu, Y., Yan, H., Song, X., Wang, Y., Li, X., & Lin, Q. (2024). Protective Effect of Protocatechuic Aldehyde on Cerebral Ischemia/Reperfusion Injury in Rats through Blood–Brain Barrier Protection. Bulletin of Experimental Biology and Medicine. https://doi.org/10.1007/s10517-024-06264-z

  • He, F., Xu, C., Feng, J., Sun, H., Yan, M., Yang, Q., Zhou, X., Yang, J., & Lin, Q. (2024). Pharmacokinetics of 4-Hydroxybenzaldehyde in Normal and Cerebral Ischemia–Reperfusion Injury Rats Based on Microdialysis Technique. European Journal of Drug Metabolism and Pharmacokinetics. https://doi.org/10.1007/s13318-023-00863-3

  • He, F., Ma, C., Feng, J., Li, X., Xia, S., Lin, Q., Dai, R., & He, F. (2021). Angiogenesis effects of 4-methoxy benzyl alcohol on cerebral ischemia-reperfusion injury via regulation of VEGF-Ang/Tie2 balance. Canadian Journal of Physiology and Pharmacology. https://doi.org/10.1139/cjpp-2021-0118

  • He, F., Dai, R., Zhou, X., Li, X., Song, X., Yan, H., Meng, Q., Yang, C., & Lin, Q. (2019). Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury. Biomedicine & Pharmacotherapy. https://doi.org/10.1016/j.biopha.2019.109260

  • He, F., Duan, X., Dai, R., Li, Y., & Lin, Q. (2017). Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood–Brain Barrier after Cerebral Ischemia Reperfusion Injury. Journal of Stroke and Cerebrovascular Diseases. https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.01.018

 

Nceba Gqaleni | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

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Prof. Nceba Gqaleni | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Research Professor at University of KwaZulu-Natal, South Africa

Professor Nceba Gqaleni is a renowned academic and researcher at the University of KwaZulu-Natal, South Africa. He currently serves as an Acting Academic Leader in the Discipline of Traditional Medicine and as a Research Professor. With a passion for integrating traditional medicine into mainstream healthcare, his research aims to address health challenges facing Africa, including HIV, diabetes, and cancer. His work on herbal treatments and immunomodulators has positioned him as a pioneer in exploring alternative therapies. Prof. Gqaleni’s research is characterized by the synergy between modern science and indigenous knowledge systems, contributing significantly to the global healthcare landscape. His work continues to impact public health, with ongoing clinical trials and innovative studies aimed at improving health outcomes. Additionally, he is committed to training the next generation of researchers, having mentored numerous postdoctoral, PhD, and master’s students.

Professional Profile

Education

Professor Nceba Gqaleni’s educational background is rooted in biochemistry, with a PhD in Biochemistry from the University of Strathclyde in Glasgow, UK. He also holds a Master’s degree in Biochemistry from the University of KwaZulu-Natal (UKZN), South Africa. His academic journey has been marked by a deep interest in both the molecular and traditional aspects of medicine, leading him to pursue research that bridges these fields. His formal education laid the foundation for a distinguished career in both academia and research, where he has applied his scientific expertise to explore alternative therapies and the integration of traditional medicine into contemporary health systems. Prof. Gqaleni’s educational path reflects a commitment to advancing knowledge and improving healthcare, particularly in the African context.

Professional Experience

Professor Gqaleni’s professional experience spans academia, research, and leadership. He currently holds the position of Acting Academic Leader in the Discipline of Traditional Medicine at the University of KwaZulu-Natal. His role involves guiding academic initiatives and research in traditional medicine, while also providing leadership in curriculum development and research supervision. In addition to his academic responsibilities, Prof. Gqaleni has led numerous significant research projects, particularly focused on traditional medicine’s role in addressing major health issues such as HIV and diabetes. His extensive work in supervising postgraduate students, including over 7 postdoctoral researchers, 12 PhD candidates, and 25 master’s students, demonstrates his dedication to nurturing the next generation of scholars and researchers. Prof. Gqaleni’s professional experience is a blend of academic excellence, mentorship, and groundbreaking research in the field of traditional medicine and biochemistry.

Research Interests

Professor Nceba Gqaleni’s research interests lie at the intersection of biochemistry and traditional medicine, with a primary focus on finding alternative treatments for diseases prevalent in Africa, such as HIV, diabetes, and cancer. He has led pioneering research on herbal compositions for the treatment of HIV and is currently conducting clinical trials for a patented HIV cure. In addition to HIV, his research extends to cancer therapies, immunomodulators, and the application of Indigenous phytotherapy in managing diseases like diabetes and HIV. Prof. Gqaleni’s ongoing research projects also explore the health and wellness of Indigenous peoples, particularly in the context of climate change and global health disparities. His work is driven by the goal of bridging the gap between traditional healing practices and modern medical approaches, thereby improving health outcomes in African communities and globally.

Awards and Honors

Professor Nceba Gqaleni’s career has been marked by significant achievements and recognition. He has been honored for his pioneering work in traditional medicine and biochemistry, particularly in the field of HIV and diabetes treatment. One of his notable accomplishments is the filing of a patent for a herbal composition aimed at curing HIV, which is currently undergoing clinical trials. Prof. Gqaleni has also received substantial funding for his research, including a $4.4 million NIH grant for a study on Indigenous phytotherapy. His contributions to science and public health have earned him the respect of both academic and medical communities. Prof. Gqaleni’s work in advancing the integration of traditional medicine into global health systems continues to garner international attention and recognition. His awards and honors reflect his exceptional leadership and groundbreaking contributions to healthcare research.

Conclusion

Professor Nceba Gqaleni demonstrates exceptional potential for the Best Researcher Award due to his innovative contributions to HIV treatment, integration of traditional medicine, and impactful mentorship. His work addresses critical health challenges in Africa, blending traditional knowledge with modern scientific methods. While broader dissemination and commercialization efforts could strengthen his profile, his contributions make him a strong contender for the award.

Publications Top Noted

  • Indigenous Medicinal Plants Used in the Management of Diabetes in Africa: 5 Years (2019–2024) in Perspective
    • Authors: Frimpong, E.K., Thembane, N., Hlatshwayo, S., Ngcobo, M., Gqaleni, N.
    • Year: 2024
    • Citations: 2
  • Review on the Anti-Hyperglycemic Potential of Psidium guajava and Seriphium plumosum L.
    • Authors: Thembane, N., Hlatshwayo, S., Ngcobo, M., Ngubane, P., Gqaleni, N.
    • Year: 2024
    • Citations: 1
  • Erratum: An in vitro study to elucidate the effects of Product Nkabinde on immune response in peripheral blood mononuclear cells of healthy donors
    • Authors: Setlhare, B., Letsoalo, M., Nkabinde, S.A., Ngcobo, M., Gqaleni, N.
    • Year: 2024
    • Citations: 0
  • An in vitro study to elucidate the effects of product Nkabinde on immune response in peripheral blood mononuclear cells of healthy donors
    • Authors: Setlhare, B., Letsoalo, M., Nkabinde, S.A., Ngcobo, M., Gqaleni, N.
    • Year: 2024
    • Citations: 1
  • Analysis of Three Species of Cassipourea Traditionally Used for Hypermelanosis in Selected Provinces in South Africa
    • Authors: Mpofana, N., Yalo, M., Gqaleni, N., Dlova, N.C., Hussein, A.A.
    • Year: 2024
    • Citations: 0
  • Melasma in People with Darker Skin Types: A Scoping Review Protocol on Prevalence, Treatment Options for Melasma, and Impact on Quality of Life
    • Authors: Mpofana, N., Chibi, B., Gqaleni, N., Kgarosi, K., Dlova, N.C.
    • Year: 2023
    • Citations: 3
  • The Effect of Melasma on the Quality of Life in People with Darker Skin Types Living in Durban, South Africa
    • Authors: Mpofana, N., Paulse, M., Gqaleni, N., Hussein, A., Dlova, N.C.
    • Year: 2023
    • Citations: 0
  • The Met and Unmet Health Needs for HIV, Hypertension, and Diabetes in Rural KwaZulu-Natal, South Africa: Analysis of a Cross-Sectional Multimorbidity Survey
    • Authors: Singh, U., Olivier, S., Cuadros, D., Ramnanan, A., Harilall, S., Gqaleni, N.
    • Year: 2023
    • Citations: 5
  • An Investigation into the Acute and Subacute Toxicity of Extracts of Cassipourea flanaganii Stem Bark In Vivo
    • Authors: Mpofana, N., Chipangura, J.K., Paulse, M., Hussein, A.A., Crouch, N.R.
    • Year: 2023
    • Citations: 2
  • Treatment of Melasma on Darker Skin Types: A Scoping Review
    • Authors: Mpofana, N., Chibi, B., Visser, T., Hussein, A.A., Dlova, N.C.
    • Year: 2023
    • Citations: 4