Dr. Yunlong Liu | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

lecturer at Tiangong university, China

Dr. Yunlong Liu is a distinguished structural biologist specializing in transcriptional regulation and nuclear receptor mechanisms. He is currently a Lecturer at Tiangong University, where he contributes to cutting-edge research in biochemistry and molecular biology. His expertise lies in protein structure determination, molecular interactions, and drug discovery, particularly in identifying potent inhibitors for nuclear receptors. With multiple high-impact publications, including Nucleic Acids Research and Cell Discovery, Dr. Liu has established himself as a promising researcher in his field. He has secured national-level research funding and actively contributes to prestigious scientific projects. Recognized for his academic excellence, he has received numerous awards, including the Outstanding Doctoral Dissertation Award and National Ph.D. Scholarship. His work not only advances fundamental biological understanding but also holds potential for therapeutic applications. With a strong foundation in research and teaching, Dr. Liu continues to make significant contributions to the field of structural biology.

Professional Profile

• ORCID Profile

Education

Dr. Yunlong Liu completed his Ph.D. in Biochemistry and Molecular Biology at China Agricultural University in 2023, where he conducted groundbreaking research on structural biology and transcriptional regulation. His doctoral work involved the determination of multiple protein and nucleic acid complex structures, providing critical insights into nuclear receptor function. During his Ph.D., he was recognized for his exceptional academic performance, receiving the Outstanding Doctoral Dissertation Award and National Ph.D. Scholarship. Prior to his doctoral studies, he earned his undergraduate degree from a prestigious institution, excelling in both coursework and research. His academic journey has been marked by a strong emphasis on molecular mechanisms and protein interactions, laying the foundation for his current research. With a solid background in structural biology and biochemistry, Dr. Liu has developed expertise in crystallography, molecular modeling, and drug discovery, positioning him as a leading researcher in his field.

Professional Experience

Dr. Yunlong Liu is currently a Lecturer in the College of Life Sciences at Tiangong University, where he teaches and mentors students in biochemistry and molecular biology. Before this role, he conducted extensive doctoral research at China Agricultural University, focusing on protein structural analysis and transcriptional regulation. His research contributions include the identification of a highly potent nuclear receptor inhibitor and the resolution of multiple protein-DNA complex structures. As a key member of several national research projects, he has played an instrumental role in advancing molecular biology research in China. He has also secured independent research funding, serving as the Principal Investigator for a National Natural Science Foundation of China project. His professional experience extends beyond academia, as his research findings have implications for pharmaceutical development and biomedical sciences. Through his teaching and research, Dr. Liu continues to shape the next generation of scientists while making significant contributions to his field.

Research Interests

Dr. Yunlong Liu’s research focuses on the molecular mechanisms of transcriptional regulation, nuclear receptor functions, and protein-nucleic acid interactions. His work in structural biology involves determining the 3D structures of key biomolecules using advanced crystallography techniques, providing crucial insights into gene regulation and disease pathways. He is particularly interested in studying nuclear receptors and their role in gene expression, with the aim of identifying novel therapeutic targets for metabolic and genetic disorders. His research has led to the discovery of a nuclear receptor inhibitor with significantly enhanced efficacy, highlighting the potential for drug development. Additionally, he explores epigenetic modifications and their structural basis, contributing to the broader understanding of gene regulation. With a strong commitment to advancing biomedical research, Dr. Liu continues to explore new methodologies and collaborative approaches to address fundamental questions in biochemistry and molecular biology.

Awards and Honors

Dr. Yunlong Liu has been widely recognized for his outstanding contributions to structural biology and molecular research. He received the Outstanding Doctoral Dissertation Award from China Agricultural University, an honor granted to only one recipient in his college. His academic excellence also earned him the National Ph.D. Scholarship, where he ranked second in his college. Throughout his career, he has been involved in prestigious research projects funded by national and provincial organizations, including the National Natural Science Foundation of China and the Tianjin Top Scientist Studio Program. His achievements in protein structure determination and transcriptional regulation have led to publications in top-tier journals such as Nucleic Acids Research and Cell Discovery. His early accomplishments include awards in mathematical modeling competitions and national scholarships during his undergraduate studies. With a track record of excellence, Dr. Liu continues to receive accolades for his impactful research and academic contributions.

Conclusion

Dr. Yunlong Liu is a strong candidate for the Best Researcher Award, given his high-impact research, prestigious awards, and leadership in structural biology. His work in transcriptional regulation and nuclear receptors is scientifically significant and widely recognized. Strengthening international collaborations, expanding independent funding, and showcasing mentorship contributions could further elevate his standing.

Publications Top Noted

1. Nucleic Acid-Based Therapies

• Title: The Progress and Evolving Trends in Nucleic-Acid-Based Therapies
• Authors: Liu, Y., Wang, C., Fu, X., & Ren, M.
• Year: 2025
• Journal: Biomolecules
• DOI: 10.3390/biom15030376

2. Nucleic Acid Recognition and 6mA Demethylation

• Title: Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A
• Authors: Shang, G., Yang, M., Li, M., Ma, L., Liu, Y., Ma, J., Chen, Y., Wang, X., Fan, S., Xie, M., et al.
• Year: 2024
• Journal: International Journal of Molecular Sciences
• DOI: 10.3390/ijms25020686

3. Transcriptional Regulation and Structural Insights

• Title: Structures of Human TR4LBD–JAZF1 and TR4DBD–DNA Complexes Reveal the Molecular Basis of Transcriptional Regulation
• Authors: Liu, Y., Ma, L., Li, M., Tian, Z., Yang, M., Wu, X., Wang, X., Shang, G., Xie, M., Chen, Y., et al.
• Year: 2023
• Journal: Nucleic Acids Research
• DOI: 10.1093/nar/gkac1259

4. Molecular Recognition of Nucleosomes

• Title: Structures of MPND Reveal the Molecular Recognition of Nucleosomes
• Authors: Yang, M., Li, X., Tian, Z., Ma, L., Ma, J., Liu, Y., Shang, G., Liang, A., Wu, W., Chen, Z.
• Year: 2023
• Journal: International Journal of Molecular Sciences
• DOI: 10.3390/ijms24043368

5. Epigenetic Functions and Nucleic Acid Repair

• Title: Structural Insights into the Interactions and Epigenetic Functions of Human Nucleic Acid Repair Protein ALKBH6
• Authors: Ma, L., Lu, H., Tian, Z., Yang, M., Ma, J., Shang, G., Liu, Y., Xie, M., Wang, G., Wu, W., et al.
• Year: 2022
• Journal: Journal of Biological Chemistry
• DOI: 10.1016/j.jbc.2022.101671

6. Protein-DNA Complex and Recognition Mechanisms

• Title: Crystal Structures of REF6 and Its Complex with DNA Reveal Diverse Recognition Mechanisms
• Authors: Tian, Z., Li, X., Li, M., Wu, W., Zhang, M., Tang, C., Li, Z., Liu, Y., Chen, Z., Yang, M., et al.
• Year: 2020
• Journal: Cell Discovery
• DOI: 10.1038/s41421-020-0150-6