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Dr. Sen Yang | Pancreatology | Best Researcher Award

MD student at Peking Union Medical College Hospital, China.

Dr. Sen Yang is a medical doctor and researcher specializing in general and pancreatic surgery at Peking Union Medical College Hospital, affiliated with the Chinese Academy of Medical Sciences. With a strong foundation in medicine from Chongqing Medical University and advanced surgical training at Qinghua University & Peking Union Medical College, Dr. Yang focuses on tumor immunology and pancreatic cancer. His career is marked by active contributions to high-impact research, particularly in tumor-associated macrophages and pancreatic cystic neoplasms. He is adept in organoid techniques and oncology experiments and has co-authored over a dozen peer-reviewed publications. Recognized for his academic excellence, Dr. Yang has received multiple awards, including a prestigious travel award from the American Pancreatic Association. His interdisciplinary expertise in clinical surgery and basic science research positions him as a promising figure in surgical oncology and translational medicine.

Professional Profile

Education

Dr. Sen Yang began his academic journey at The Affiliated High School of Sichuan University. He pursued his undergraduate studies in medicine at Chongqing Medical University (2015–2020), where he built a foundation in biochemistry, genetics, immunology, and clinical medicine. He then advanced to a master’s program in surgery at Qinghua University & Peking Union Medical College (2020–2023), receiving extensive clinical training in general, cardiothoracic, neurosurgery, and anesthesiology. Currently, he is enrolled in a Medical Doctor (MD) program at the same institution, specializing in pancreatic surgery. His training encompasses both professional surgical skills and basic research methodologies. Throughout his educational trajectory, Dr. Yang has demonstrated a keen interest in translational research, combining academic rigor with hands-on clinical experience. This multidisciplinary education has laid the groundwork for his impactful work in surgical oncology and tumor immunology, particularly within the field of pancreatic diseases.

Professional Experience

Since 2020, Dr. Sen Yang has been a research associate at the State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital. His work primarily focuses on tumor immunology, especially pancreatic cancer and cystic neoplasms. He investigates tumor-associated macrophages, biomarkers, and carcinogenic mechanisms using organoid models and advanced cytological techniques. Prior to this, from 2015 to 2020, he conducted liver immunoinflammatory pharmacology research at the Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing Medical University. There, he developed strong skills in molecular biology methods such as PCR, IHC, and Western blotting. Dr. Yang has contributed to over 20 peer-reviewed articles and has become proficient in translating complex biological questions into experimental designs. His experience blends clinical training with laboratory excellence, making him a dynamic contributor to both research and patient care in oncology.

Research Interests

Dr. Sen Yang’s primary research interests lie in pancreatic cancer, tumor immunology, and organ-specific pathology. At the State Key Laboratory of Complex Severe and Rare Diseases, he explores the role of tumor-associated macrophages in pancreatic ductal adenocarcinoma, delving into their origin, polarization, and immunomodulatory functions. His work involves biomarker screening, especially for pancreatic cystic neoplasms, and understanding their underlying mechanisms of carcinogenesis. He has hands-on expertise in organoid cultures, single-cell RNA sequencing, and immunohistochemical techniques. Previously, his focus at Chongqing Medical University was on liver immunoinflammatory pharmacology, specifically how compounds modulate inflammatory responses in hepatic cells. Across his research portfolio, Dr. Yang aims to translate fundamental insights into therapeutic strategies that bridge laboratory innovations with clinical applications. His integrative approach, spanning molecular biology and clinical relevance, makes significant contributions to the future of personalized oncology and surgical intervention.

Awards and Honors

Dr. Sen Yang’s academic and research excellence has been recognized with multiple prestigious awards. In 2022, he received a Travel Award from the American Pancreatic Association (APA) for outstanding research contributions, ranking in the top 20% of poster presentations. He also delivered an oral presentation at the 53rd Annual Meeting of the Japan Pancreas Society, showcasing his clinical insights and scientific innovation. Dr. Yang has been consistently honored with academic scholarships from Peking Union Medical College and Beijing Union Medical College Hospital during 2020–2022 for his strong academic standing and research achievements. His dedication to pancreatic disease research and high-impact presentations at international forums reflect his growing reputation as a promising young leader in the medical research community. These accolades underscore not only his intellectual merit but also his commitment to pushing the boundaries of translational medicine and surgery.

Conclusion

Dr. Sen Yang is highly suitable for the Best Researcher Award, especially in the category of early-career or emerging investigators. His deep engagement in high-impact pancreatic cancer research, proven publication record, and international recognition align well with the award’s prestige. With ongoing contributions and leadership development, he is poised to become a prominent figure in surgical oncology and tumor immunology.

Publications Top Notes

  • Advanced insights on tumor-associated macrophages revealed by single-cell RNA sequencing

    • Authors: Yang S, Wang M, Hua Y, et al.

    • Year: 2024

    • Journal: Cancer Letters

    • DOI: 10.1016/j.canlet.2024.216610

    • PMID: 38244910

  • Glycosylation of immunoglobin G in tumors: Function, regulation and clinical implications

    • Authors: Yang S, Cui M, Liu Q, Liao Q

    • Year: 2022

    • Journal: Cancer Letters

    • DOI: 10.1016/j.canlet.2022.215902

  • Tumor-Associated Macrophages in Pancreatic Ductal Adenocarcinoma

    • Authors: Yang S, Liu Q, Liao Q

    • Year: 2021

    • Journal: Frontiers in Cell and Developmental Biology

    • DOI: 10.3389/fcell.2020.607209

  • GREM1 as a novel serum diagnostic marker for pancreatic ductal adenocarcinoma

    • Authors: Yang S, Zhang Y, Hua Y, et al.

    • Year: 2022

    • Journal: Frontiers in Oncology

    • DOI: 10.3389/fonc.2022.968610

  • Long-term Sustained Clinical Remission of Peritoneal Metastatic Pancreatic Ductal Adenocarcinoma

    • Authors: Yang S, Hua Y, Liu Q, Liao Q

    • Year: 2024

    • Journal: Journal of Pancreatology

    • DOI: 10.1097/JP9.0000000000000172

  • Mangiferin Attenuates LPS/D-GalN-Induced Acute Liver Injury

    • Authors: Yang S, Kuang G, Zhang L, et al.

    • Year: 2020

    • Journal: Frontiers in Immunology

    • DOI: 10.3389/fimmu.2020.00285

    • PMID: 32158448

  • Geniposide protected hepatocytes from acetaminophen hepatotoxicity

    • Authors: Yang S, Kuang G, Jiang R, et al.

    • Year: 2019

    • Journal: International Immunopharmacology

    • DOI: 10.1016/j.intimp.2019.05.010

  • Modulating ferroptosis sensitivity in the tumor microenvironment

    • Authors: Hua Y, Yang S, Zhang Y, et al.

    • Year: 2024

    • Journal: Journal of Experimental & Clinical Cancer Research

    • DOI: 10.1186/s13046-023-02925-5

    • PMID: 38217037

  • Comprehensive analysis of MiNENs: A SEER database analysis

    • Authors: Song H, Yang S, Zhang Y, et al.

    • Year: 2023

    • Journal: Frontiers in Oncology

    • DOI: 10.3389/fonc.2022.1007317

  • CD58 Immunobiology at a Glance

    • Authors: Zhang Y, Liu Q, Yang S, Liao Q

    • Year: 2021

    • Journal: Frontiers in Immunology

    • DOI: 10.3389/fimmu.2021.705260

  • Knockdown of LRRN1 in pancreatic ductal adenocarcinoma

    • Authors: Zhang Y, Liu Q, Yang S, Liao Q

    • Year: 2021

    • Journal: Molecular Therapy Oncolytics

    • DOI: 10.1016/j.omto.2021.08.012

  • Paeonol alleviates liver fibrosis via TGF-β/Smad3 signaling

    • Authors: Wu S, Liu L, Yang S, et al.

    • Year: 2019

    • Journal: Immunopharmacology and Immunotoxicology

    • DOI: 10.1080/08923973.2019.1613427

  • Adoptive cellular immunotherapy for solid neoplasms

    • Authors: Liu Q, Li J, Zheng H, Yang S, et al.

    • Year: 2023

    • Journal: Molecular Cancer

    • DOI: 10.1186/s12943-023-01735-9

  • Local resection for solid pseudopapillary neoplasms of the pancreas

    • Authors: Hua Y, Hong X, Dai M, Yang S, et al.

    • Year: 2023

    • Journal: International Journal of Surgery

    • DOI: 10.1097/JS9.0000000000000702

  • Cell diversity and immune infiltration in parathyroid tumors

    • Authors: Zhang X, Hu Y, Cui M, Yang S, et al.

    • Year: 2023

    • Journal: Endocrine-Related Cancer

    • DOI: 10.1530/ERC-22-0325

  • Long-term Survival and QoL in Solid Pseudopapillary Neoplasm of the Pancreas

    • Authors: Liu Q, Dai M, Guo J, Yang S, et al.

    • Year: 2023

    • Journal: Annals of Surgery

    • DOI: 10.1097/SLA.0000000000005842

Sen Yang | Pancreatology | Best Researcher Award

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