reyhaneh nassiri mansour | Regenerative medicine | Women Researcher Award

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Dr. Reyhaneh nassiri mansour | regenerative medicine | Women Researcher Award

post doc, immunogenetic institue, Iran

Profile

Orcid

Short Bio 🌱

Reyhaneh Nassiri Mansour, born on June 5, 1986, in Tehran, Iran, is a clinical biochemist with a strong academic background and hands-on experience in stem cell research. With a focus on cancer research and regenerative medicine, she has contributed to significant advancements in biotechnology, particularly in the differentiation of stem cells into insulin-producing cells. Reyhaneh is an educator and researcher passionate about the interface of clinical biochemistry and molecular biology. She has published several peer-reviewed articles and presented her findings at international conferences.

Education 🎓

Reyhaneh completed her B.Sc. in General Biology from Islamic Azad University, North Tehran Branch, in 2008. She further pursued an M.Sc. in Clinical Biochemistry at Zanjan University of Medical Sciences (2012-2015), where her thesis focused on the expression levels of HIF-1 alpha gene in colorectal cancer stages. Her academic work under the supervision of Dr. Mojtaba Fathi fueled her interest in gene expression and stem cell therapy.

Experience 🧪

Reyhaneh has held multiple roles in academia and industry, contributing to her diverse skill set. She has worked as a research employee at Livogen Pharmed Co. and as a trainee at the Stem Cell Research Technology Center. With a deep understanding of laboratory techniques, including DNA extraction, real-time PCR, and stem cell culture, she has also taught General Biochemistry to B.Sc. students across various health disciplines at Zanjan University of Medical Sciences.

Research Interests 🔬

Her research interests span stem cell therapy, gene expression, and cancer research. She has focused on developing insulin-producing cells from human-induced pluripotent stem cells (hiPSCs) and exploring the role of hypoxia-inducible factor-1 alpha in cancer. Reyhaneh is also invested in using tissue engineering and scaffolds for regenerative medicine.

Publications Top Notes 📚

  1. Evaluation of hypoxia-inducible factor-1 alpha gene expression in colorectal cancer stages of Iranian patients. Mansour RN, et al. J Cancer Res Ther. 2016; 12(4):1313-1317. DOI: 10.4103/0973-1482.199542 (Cited by 15 articles)
  2. Generation of high-yield insulin producing cells from human-induced pluripotent stem cells on polyethersulfone nanofibrous scaffold. Mansour RN, et al. Artif Cells Nanomed Biotechnol. 2018. DOI: 10.1080/21691401.2018.1434663 (Cited by 32 articles)
  3. Collagen-coated electrospun polyethersulfone nanofibers improved insulin-producing cells’ differentiation potential of human induced pluripotent stem cells. Mansour RN, et al. Artif Cells Nanomed Biotechnol. 2018. DOI: 10.1080/21691401.2018.1508031 (Cited by 25 articles)
  4. Improved stem cell therapy of spinal cord injury using GDNF-overexpressed bone marrow stem cells in a rat model. Shahrezaei M, Mansour RN, et al. Biologicals. 2017. DOI: 10.1016/j.Biologicals.2017.08.009 (Cited by 18 articles)
  5. Improved osteogenic differentiation of human induced pluripotent stem cells cultured on poly vinylidene fluoride/collagen/platelet-rich plasma composite nanofibers. Mansour RN, et al. J Cell Physiol. 2019. DOI: 10.1002/jcp.29029 (Cited by 20 articles)
  6. Generation of insulin-producing cells from human-induced pluripotent stem cells on PLLA/PVA nanofiber scaffold. Mansour RN, et al. Artif Cells Nanomed Biotechnol. 2018. DOI: 10.1080/21691401.2018.1443466 (Cited by 28 articles)
  7. In vitro osteogenic differentiation potential of human induced pluripotent stem cells augmented on graphene oxide-modified nanofibers. Mansour RN, et al. Gene. 2019. DOI: 10.1016/j.gene.2019.02.028 (Cited by 16 articles)
  8. Glioblastoma: Exosome and microRNA as novel diagnostic biomarkers. Mansour RN, et al. Cancer Gene Ther. 2016. DOI: 10.1038/cgt.2016.48 (Cited by 30 articles)

Magdalena Zernicka Goetz | Stem cell biology | Breakthrough Innovator Award

Published on by World Top Scientists

Prof. Magdalena Zernicka-Goetz | Stem cell biology | Breakthrough Innovator Award

Professor, California Institute of Technology, United States

Magdalena Zernicka-Goetz, Ph.D., is a distinguished Bren Professor of Biology and Biological Engineering at the California Institute of Technology (Caltech), USA, and a Professor in Mammalian Development and Stem Cell Biology at the University of Cambridge, UK. 🌍 With an extensive background in physiology, development, and neuroscience, she has made remarkable contributions to the field. 🧬 As a Fellow of Sidney Sussex College, Cambridge, she balances her academic pursuits with a personal life, being a proud mother to Natalia (born 2001) and Szymon (born 2007). 🌈 Driven by her passion for science and family, she continues to inspire in both academic and personal realms. 🚀

Profile

google scholar

Education

Magdalena Zernicka-Goetz’s academic journey is a testament to her commitment and excellence. 🎓 She earned her Master of Science in Developmental Biology with summa cum laude honors from the University of Warsaw in 1988. 🏆 Continuing her pursuit of knowledge, she completed her Ph.D. in Developmental Biology of Mammals at the same institution under the guidance of Prof. Andrzej Tarkowski. 🧬 Her scholarly pursuits extended internationally with a SOROS Foundation Fellowship at the University of Oxford in 1990-1991 and an EMBO Fellowship at the University of Cambridge in 1995-1997 under the mentorship of Prof. Chris Graham and Prof. Martin Evans, respectively. 🌍 This diverse academic background laid the foundation for her groundbreaking contributions in developmental biology. 🚀

Awards and Honours

Magdalena Zernicka-Goetz stands as a distinguished figure in the scientific community, adorned with numerous accolades that highlight her exceptional contributions to stem cell research and developmental biology. 🏅 Among her recent honors, the Ogawa-Yamanaka Stem Cell Prize in 2023 and the Edwin G. Conklin Medal in 2022 underscore her groundbreaking work. 🌟 The NIH Director’s Pioneer Award in 2020 and her tenure as the Chih-Ye Professor at the State Key Laboratory of Stem Cell and Reproductive Biology in Beijing further emphasize her global impact. 🌍 Over the years, she has garnered recognition for her lifetime contributions, including COGI and RBMO awards, the International Foundation IVI Award, and being the People’s Vote winner for Scientific Breakthrough of the Year in 2016. 🚀 Her journey, marked by prestigious fellowships and awards, reflects a career dedicated to advancing scientific knowledge.

Professional History 

Magdalena Zernicka-Goetz’s illustrious career has been marked by significant milestones and academic achievements. 🌟 Since 2010, she has held the position of Professor in Mammalian Development and Stem Cell Biology at the University of Cambridge, contributing to the Department of Physiology, Development & Neuroscience. 🎓 Her commitment to academic excellence was acknowledged with tenure as Reader in Developmental Biology from 2007 to 2010. 🏆 Zernicka-Goetz’s leadership flourished as a Group Leader at the Wellcome Trust/Cancer Research Institute from 2003, and her role as a Wellcome Trust Senior Research Fellow from 2003 to 2023 underscores her influential presence in scientific research. 🚀 Additionally, she became a Fellow of Sidney Sussex College in 2016, further enriching the academic tapestry at Cambridge. 🎓

Publications Top Notes

  1. “Specific interference with gene function by double-stranded RNA in early mouse development”
  2. “G&T-seq: parallel sequencing of single-cell genomes and transcriptomes”
  3. “Self-organization of the in vitro attached human embryo”
    • Publication Link: Nature
    • Cited By (Year): 656 (2016)
  4. “Histone arginine methylation regulates pluripotency in the early mouse embryo”
    • Publication Link: Nature
    • Cited By (Year): 648 (2007)
  5. “Self-organization of the human embryo in the absence of maternal tissues”
  6. “A genome-wide study of gene activity reveals developmental signaling pathways in the preimplantation mouse embryo”
  7. “Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation”
    • Publication Link: Cell
    • Cited By (Year): 430 (2014)
  8. “Heterogeneity in Oct4 and Sox2 targets biases cell fate in 4-cell mouse embryos”
    • Publication Link: Cell
    • Cited By (Year): 414 (2016)
  9. “Citrullination regulates pluripotency and histone H1 binding to chromatin”
    • Publication Link: Nature
    • Cited By (Year): 412 (2014)
  10. “Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro”
    • Publication Link: Science
    • Cited By (Year): 399 (2017)