Hao Yang | Neuroscience | Best Researcher Award

Prof. Hao Yang | Neuroscience | Best Researcher Award

Distinguished professor at Yang Soochow University, China

Dr. Hao Yang is a distinguished professor and leading neuroscientist specializing in stem cell therapy for central nervous system (CNS) injuries and neurodegenerative diseases. Currently serving as Director of the Translational Medicine Center at Honghui Hospital, Xi’an Jiaotong University, he has made significant contributions to regenerative medicine, particularly in reprogramming mesenchymal stem cells (MSCs) and astrocytes for functional recovery in spinal cord injury. With over 90 SCI-indexed publications—more than 60 as first or corresponding author—and a total impact factor exceeding 330, his research is widely recognized, earning over 3,700 citations in high-impact journals such as Nature Neuroscience, Cell, and Neuron. Dr. Yang has led 13 major research projects and holds editorial and reviewer roles in several international journals. He has been honored with multiple national awards, including the Provincial First Prize for Scientific Progress and the Gusu Talent Award, reflecting his leadership and innovation in translational neuroscience.

Professional Profile 

ORCID Profile 

Education

Dr. Hao Yang earned his Ph.D. in Neurobiology in 2007 from the prestigious Fourth Military Medical University (FMMU), under the mentorship of Academician Ju Gong, a renowned neuroscientist. His strong academic foundation was further enriched through international postdoctoral training. In 2010, he joined Emory University in the United States as a Postdoctoral Fellow, gaining exposure to cutting-edge neuroscience research. He later enhanced his global academic experience as a Visiting Scholar at Loma Linda University in 2015. This diverse educational background, combining rigorous Chinese academic traditions with Western biomedical research approaches, laid the groundwork for his expertise in neuroregeneration and stem cell therapy. Dr. Yang’s educational journey reflects a strategic focus on translational neuroscience, bridging theoretical insights and clinical application. His training under leading scientists and at world-class institutions has significantly shaped his scientific vision and capacity for innovative research in central nervous system repair and regenerative medicine.

Professional Experience

Dr. Hao Yang has held several key academic and research leadership roles throughout his career. Following completion of his Ph.D., he joined the faculty of the Fourth Military Medical University, where he began building his research credentials. From 2012 to 2016, he served as Principal Investigator at the Stem Cell Research Center of Renji Hospital, affiliated with Shanghai Jiao Tong University School of Medicine, where he led pioneering work in regenerative therapies. Since 2016, he has been the Director of the Translational Medicine Center at Honghui Hospital, affiliated with Xi’an Jiaotong University, where he leads multidisciplinary teams in translational neuroscience. He also holds the title of Distinguished Professor at Soochow University and Adjunct Professor at Ningxia Medical University. These positions reflect his strong academic reputation and leadership in advancing stem cell therapy and neurorepair research. Dr. Yang’s professional journey demonstrates a consistent upward trajectory marked by innovation, leadership, and impactful collaboration.

Research Interest

Dr. Hao Yang’s research focuses on developing novel stem cell-based therapies for central nervous system (CNS) injuries and neurodegenerative diseases. His pioneering work integrates tissue engineering with stem cell biology to enhance neural repair and functional recovery. A key area of his research involves reprogramming mesenchymal stem cells (MSCs) and astrocytes into neural stem cells and neurons, aiming to treat spinal cord injuries more effectively. He also investigates MSC paracrine effects and their application in osteochondral degeneration, often incorporating platelet-rich plasma (PRP) technologies to enhance regenerative outcomes. Dr. Yang’s studies bridge fundamental neuroscience and clinical application, contributing to the emerging field of translational medicine. His work not only explores cell-based mechanisms of regeneration but also emphasizes therapeutic strategies that are clinically viable. By combining cellular reprogramming, biomaterials, and advanced delivery systems, his research continues to push the boundaries of what is possible in functional neural restoration.

Award and Honor

Dr. Hao Yang has received multiple prestigious awards and recognitions that underscore his contributions to neuroscience and regenerative medicine. In 2016, he was honored with the Provincial/Ministerial First Prize for Scientific Progress, highlighting the societal impact of his research. That same year, he earned a Third-Class Military Merit Citation for his academic excellence within the military medical system. In 2015, he was selected as a “100 Talents” Reserve Scholar by Shanghai Jiao Tong University, one of China’s most competitive academic honors. More recently, he was awarded the Gusu Talent Award and named a Leading Young Talent at Honghui Hospital in 2022, reflecting his continuing leadership in the field. In addition to accolades, he serves on multiple academic committees and grant review panels, including the NSFC and Ministry of Education. These honors affirm his scientific leadership, research innovation, and ongoing contributions to the advancement of medical science in China and beyond.

Conclusion

In summary, Dr. Hao Yang is a highly accomplished neuroscientist and research leader whose work in stem cell therapy and CNS regeneration has made significant scientific and clinical impacts. With a solid educational foundation, international research experience, and a series of prominent academic appointments, he has established himself as a leading figure in translational medicine. His research, which combines cellular reprogramming, biomaterials, and regenerative biology, addresses critical unmet needs in neural repair and neurodegeneration. Dr. Yang’s achievements are further reflected in his extensive publication record, competitive research funding, and numerous national honors. His leadership roles, including director-level appointments and editorial board service, demonstrate a deep commitment to scientific advancement and collaboration. While he continues to expand his global influence, his current body of work firmly establishes him as a top-tier researcher. Dr. Yang is exceptionally well-qualified for high-level scientific recognition, including consideration for the Best Researcher Award.

Publications Top Notes

1. Aberrant Development of Hippocampal GABAergic Neurons Arising from Hypothyroidism Contributes to Memory Deficits in Mice Through Maf Suppressing Mef2c

  • Authors: Mengyan Wu; Xingdong Zeng; Yongle Cai; Haonan Chen; Hao Yang

  • Year: 2025 (June 11)

2. Therapeutic Potential of Mesenchymal Stem Cell‑Derived Exosomes in Spinal Cord Injury

  • Authors: Jing An; Bo Chen; Rui Zhang; Ding Tian; Kuohao Shi; Lingling Zhang; Gaorong Zhang; Jingchao Wang; Hao Yang

  • Year: 2025 (January)

3. Advances in Genetically Modified Neural Stem Cell Therapy for Central Nervous System Injury and Neurological Diseases

  • Authors: Xiangwen Tang; Peng Deng; Lin Li; Yuqing He; Jinchao Wang; Dingjun Hao; Hao Yang

  • Year: 2024 (December 18)

4. An Overview of Current Advances in Perinatal Alcohol Exposure and Pathogenesis of Fetal Alcohol Spectrum Disorders

  • Authors: Xingdong Zeng; Yongle Cai; Mengyan Wu; Haonan Chen; Miao Sun; Hao Yang

  • Year: 2024 (April 20)

5. The Neuroprotective Role of Fisetin in Different Neurological Diseases: a Systematic Review

  • Authors: Yizhen Jiang; Xiangwen Tang; Peng Deng; Chao Jiang; Yuqing He; Dingjun Hao; Hao Yang

  • Year: 2023 (November)

6. An Overview of Recent Advances in the Neuroprotective Potentials of Fisetin …

  • Authors: Xiangwen Tang; Peng Deng; Yizhen Jiang; Lingling Zhang; Yuqing He; Hao Yang

  • Year: 2023 (October)

7. The aOECs Facilitate the Neuronal Differentiation of Neural Stem Cells …

  • Authors: Yuqing He; Yizhen Jiang; Lianwei Dong; Chao Jiang; Lingling Zhang; Gaorong Zhang; Hao Yang; Juan Liu

  • Year: 2023 (February)

8. The Anti‑inflammation Property of Olfactory Ensheathing Cells in Neural Regeneration After Spinal Cord Injury

  • Authors: Chao Jiang; Xiaohui Wang; Yizhen Jiang; Zhe Chen; Yongyuan Zhang; Dingjun Hao; Hao Yang

  • Year: 2022 (October)

9. Tetramethylpyrazine Induces the Release of BDNF from BM‑MSCs …

  • Authors: Bo Chen; Jing An; Yun-Shan Guo; Juan Tang; Jing-Jing Zhao; Rui Zhang; Hao Yang

  • Year: 2021 (December)

10. The Involvement of Bioactive Factors in the Self‑Renewal … of Spermatogonial Stem Cells

  • Authors: Guoqing Yang; Yuqing He; Hao Yang

  • Year: 2021 (April)

11. Generation of Functional Dopaminergic Neurons from Human Spermatogonial Stem Cells …

  • Authors: Hao Yang; Dingjun Hao; Cheng Liu; Dageng Huang; Bo Chen; Hong Fan; Cuicui Liu; Lingling Zhang; Qian Zhang; Jing An et al.

  • Year: 2019 (December)

12. Sonic Hedgehog Improves the Reprogramming of Oct‑4‑Mediated Astrocytes …

  • Authors: (includes) Hao Yang

  • Year: 2019 (August 10)

Hengbing Zu | Neuroscience | Best Researcher Award

Prof. Dr. Hengbing Zu | Neuroscience | Best Researcher Award

Professor at Jinshan Hospital affiliated to Fudan University, Shanghai, China

Dr. Hengbing Zu is a distinguished neurologist with over 30 years of academic and research experience. He earned his Bachelor’s degree from Anhui Medical University, his Master’s in Neurology from Shanghai Jiao Tong University School of Medicine, and his Doctorate from Fudan University’s Shanghai Medical College. As a professor and dean at the Department of Neurology, Jinshan Hospital of Fudan University, Dr. Zu has dedicated over two decades to researching the relationship between altered brain cholesterol metabolism and the pathogenesis of Alzheimer’s disease (AD). His pioneering work suggests that brain neuronal cholesterol deficiency is a shared neurochemical mechanism in both Familial and Sporadic AD. Through in-vitro studies, he demonstrated that cholesterol deficiency can trigger key pathological features of AD, including Aβ generation, tau hyperphosphorylation, and neuroinflammation. Dr. Zu’s unified “AD-cholesterol hypothesis” offers a novel perspective on AD progression, making significant contributions to the field of neurodegenerative disease research.

Professional Profile 

Scopus Profile

Education

Dr. Hengbing Zu has a strong and comprehensive educational background in clinical medicine and neurology. He obtained his Bachelor of Medicine from Anhui Medical University between 1981 and 1986, laying a solid foundation in medical sciences. He continued his academic journey by pursuing a Master’s degree in Neurology at Shanghai Jiao Tong University School of Medicine from 1996 to 1999, where he deepened his specialization in neurological disorders. Seeking to further advance his expertise, Dr. Zu earned his Doctor of Medicine degree in Neurology at the prestigious Shanghai Medical College of Fudan University from 2007 to 2011. His educational progression across top Chinese institutions reflects both his dedication to continuous learning and his commitment to excelling in the field of neurology. This extensive academic preparation has equipped Dr. Zu with a strong theoretical and practical understanding, which has underpinned his later research innovations in Alzheimer’s disease and neurodegenerative disorders.

Professional Experience

Dr. Hengbing Zu is an experienced academic leader and clinical practitioner with over three decades of service in neurology. He currently serves as a Professor and Dean of the Department of Neurology at Jinshan Hospital, affiliated with Fudan University. In this capacity, Dr. Zu oversees clinical services, research programs, and educational initiatives, playing a pivotal role in shaping the department’s strategic direction. His professional career has been distinguished by a strong focus on integrating clinical practice with research, especially in neurodegenerative diseases. Dr. Zu has consistently contributed to advancing neurological care by combining patient-centered treatment with cutting-edge scientific research. His leadership has helped foster an environment that promotes both academic inquiry and clinical excellence. Throughout his career, he has mentored young researchers, collaborated across disciplines, and worked to enhance the understanding and management of Alzheimer’s disease. His extensive experience solidifies his reputation as a respected figure in Chinese neurology.

Research Interest

Dr. Hengbing Zu’s primary research interest centers on the neurochemical mechanisms underlying Alzheimer’s disease (AD), with a particular focus on brain cholesterol metabolism. For over twenty years, he has explored how alterations in neuronal cholesterol contribute to the onset and progression of both Familial and Sporadic forms of AD. His groundbreaking work demonstrated that a deficiency in brain neuronal cholesterol can induce AD-associated pathological processes such as amyloid-beta accumulation, tau hyperphosphorylation, and neuroinflammation. Based on these findings, Dr. Zu proposed the unified “AD-cholesterol hypothesis,” suggesting that neuronal cholesterol deficiency could be a common pathogenic mechanism for all types of AD. His research bridges basic science with potential clinical applications, offering new perspectives for understanding, diagnosing, and eventually treating Alzheimer’s disease. Dr. Zu’s dedication to unraveling the molecular basis of AD has positioned him as a leading figure in cholesterol-related neurodegenerative research, significantly advancing knowledge in this critical area.

Award and Honor

Although specific awards and honors were not detailed in the provided information, Dr. Hengbing Zu’s academic and professional standing suggest a high level of recognition within his field. Serving as the Professor and Dean of the Department of Neurology at a leading university hospital indicates his peers’ strong acknowledgment of his contributions to neurology and research. It is reasonable to infer that he has been honored for his long-term dedication to Alzheimer’s disease research and academic leadership. His original proposal of the “AD-cholesterol hypothesis” represents a major intellectual achievement likely recognized through institutional and possibly national awards. In addition to formal accolades, Dr. Zu’s influence is reflected in the respect he commands within academic and medical communities. Future nominations and recognitions at the international level could further highlight his critical contributions to understanding neurodegenerative diseases, reinforcing his stature as a thought leader in neuroscience research.

Conclusion

In conclusion, Dr. Hengbing Zu is an outstanding researcher, clinician, and academic leader whose career has been dedicated to advancing the field of neurology. Through his extensive education, clinical practice, and innovative research, he has made a lasting impact on the understanding of Alzheimer’s disease, particularly through his development of the “AD-cholesterol hypothesis.” His professional experience reflects a seamless blend of clinical excellence and scientific inquiry, ensuring that his research remains deeply connected to patient needs. Dr. Zu’s long-standing focus on brain cholesterol metabolism in AD has opened new avenues for diagnosis and potential treatment strategies. Although further global recognition could strengthen his profile, his current achievements already place him among the leading experts in his field. Dr. Zu’s contributions exemplify the spirit of scientific advancement and dedication, making him a highly deserving candidate for awards recognizing excellence in research and innovation in neurological sciences.

Publications Top Notes

  • Title: New insight into the role of altered brain cholesterol metabolism in the pathogenesis of AD: A unifying cholesterol hypothesis and new therapeutic approach for AD

    • Authors: Yang, Xiaobo; Yao, Kai; Zhang, Mengqi; Zhang, Wenbin; Zu, Hengbing

    • Year: 2025

  • Title: Cellular Cholesterol Loss Impairs Synaptic Vesicle Mobility via the CAMK2/Synapsin-1 Signaling Pathway

    • Authors: Qurban, Atikam; Zhang, Mengqi; Zu, Hengbing; Yao, Kai

    • Journal: Frontiers in Bioscience

    • Year: 2025

  • Title: The association between plasma trans-fatty acids level and migraine: A cross-sectional study from NHANES 1999–2000

    • Authors: Yao, Kai; Zu, Hengbing

    • Journal: Prostaglandins, Leukotrienes and Essential Fatty Acids

    • Year: 2024