Head of Cardioprotection Group, University of Cape Town, South Africa
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Prof. Dr. Sandrine Lecour
🌟 Short Bio:
Prof. Dr. Sandrine Lecour is a distinguished researcher and educator in the field of cardiovascular physiology and pharmacology. With extensive experience in cardioprotection and innovative research methods, she currently serves as the Deputy Director and Full Professor at the Hatter/Cape Heart Institute for Cardiovascular Research at the University of Cape Town. Her work has significantly contributed to understanding the mechanisms of cardiac injury and protection, impacting clinical practice and patient care.
📚 Education:
- PhD in Cardiovascular Physiology and Pharmacology
University of Burgundy, France
Thesis Title: Role of myocardial irradiation on nitric oxide metabolism
Year: 2000
- MSc in Cardiovascular Physiology and Pathology
University of Lariboisière, Paris, France
Year: 1995
- Doctor in Pharmacy
University of Burgundy, France
Year: 1996
- French Baccalauréat in Chemistry, Mathematics, and Physics
Year: 1988 (with distinction)
💼 Employment History:
- 2017 – Present: Deputy Director, Full Professor, Hatter/Cape Heart Institute for Cardiovascular Research, University of Cape Town
- 2015 – Present: Director, Lionel Opie Preclinical Imaging Core Facility, University of Cape Town
- 2009 – 2016: Deputy Director, Associate Professor, Hatter Institute for Cardiovascular Research, University of Cape Town
- 2009 – Present: Head of the Cardioprotection Group, Hatter Institute for Cardiovascular Research, University of Cape Town
- 2010 – 2012: Co-Director, Medical Research Council Cape Heart Group
- 2005 – 2009: Deputy Director and Senior Lecturer, Hatter Institute for Cardiovascular Research, University of Cape Town
🔬 Research Interests:
Prof. Lecour’s research focuses on cardioprotection mechanisms, the pharmacological modulation of cardiac injury, and innovative imaging techniques for cardiovascular research. Her work encompasses exploring the interactions between cardiovascular risk factors and cardioprotective strategies, as well as the effects of various therapies on heart health.
🏆 Awards:
- 2022: Oppenheimer Memorial Trust Fellow Award
- 2022: B-rating, National Research Foundation Rated Researcher Award
- 2016: Louis Vogelpoel Award
- 2012: University of Cape Town Research Merit Award
- 2011: Fellow of the European Society of Cardiology (FESC)
- 2010: Claude Leon Foundation Merit Award
- 2007: University of Cape Town Fellows Award
- 2007: Vogelpoel Travel Award, South African Heart Association
- 2006-2010: Medical Research Council of South Africa Career Award
- 2005-2018: Y-rating, National Research Foundation Rated Researcher Award
- 2003: Discovery Health Clinical Excellence Award, Best oral presentation, SA Heart Meeting
- 2001: Young Investigator Award, American Heart Association, Los Angeles, USA
📖 Publications Top Notes:
- Stevic N, et al. “Effect of ventricular fibrillation on infarct size after myocardial infarction: A translational study.” Basic Research in Cardiology, 2024, in revision.
- Cour M, et al. “Interplay between the SAFE and the sphingolipid pathway for cardioprotection.” Life Sciences, 2024, accepted for publication.
- Hadebe N, et al. “Cardioprotection with Intralipid During Coronary Artery Bypass Grafting Surgery on Cardiopulmonary Bypass: A Randomized Clinical Trial.” Cardiovascular Drugs and Therapy, 2024. doi: 10.1007/s10557-024-07594-w.
- Frias MA, et al. “People living with HIV display increased anti-apolipoprotein A1 auto-antibodies, inflammation, and kynurenine metabolites: a case-control study.” Frontiers in Cardiovascular Medicine, 2024.
- Belger C, et al. “Doxorubicin-induced cardiotoxicity and risk factors.” International Journal in Cardiology Heart and Vasculature, 2024.
- Kelly-Laubscher R, et al. “Role of nuclear factor kappa-B in TNF-induced cytoprotection.” Cardiovascular Journal of Africa, 2023.
- Ferdinandy P, et al. “Interaction of cardiovascular nonmodifiable risk factors, comorbidities and comedications with ischemia/reperfusion injury and cardioprotection by pharmacological treatments and ischemic conditioning.” Pharmacological Reviews, 2023.
- Lukhna K, et al. “Effect of Remote Ischaemic Conditioning on the Inflammatory Cytokine Cascade of COVID-19 (RIC in COVID-19): a Randomized.” [Journal Title, Year] – More details needed